Amitiza Oral Amitiza口腔

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Thursday, 25 October 2007星期四， 2007年10月25

LUBIPROSTONE - ORAL LUBIPROSTONE -口服

Pronunciation: (loo-bi-PROST-own) 发音：（厕所，双向普罗斯特拥有）

Brand Name(s): Amitiza 品牌名称（星期日）： Amitiza

Uses 利用

This medication is used to treat a certain type of constipation (chronic idiopathic constipation).这种药物是用来治疗某些类型的便秘（慢性特发性便秘）。 This type of constipation has an unknown cause and is not due to diet, other diseases, or drugs.这种类型的便秘有一个不明原因，是不是因为饮食习惯，其他疾病或药物。 This medication may improve symptoms such as bloating and abdominal discomfort, improve stool texture, lessen the need to strain, and decrease the feeling of not completely relieving oneself.这种药物可改善症状，如腹胀和腹部不适，改善大便质地，减少需要应变，减少的感觉没有完全缓解自己。 Lubiprostone belongs to a class of drugs known as chloride channel activators. Lubiprostone属于一类的药物被称为氯离子通道激活。 It works by increasing the amount of fluid within your intestines, making the passage of stool easier.它的工作原理是越来越多的液量在您的肠道，使粪便通过比较容易。

How to use Amitiza Oral 如何使用口服Amitiza

Take this medication by mouth with food, usually twice daily or as directed by your doctor.借此药物经口食物，通常每天有两次或由您的医生。

Use this medication regularly in order to get the most benefit from it.使用此药定期举行，以便获得最大的受益。 Remember to take it at the same times each day.请记住，是否可以在同一时间每一天。

You should talk to your doctor regularly about whether you still need this treatment.你应该谈论你的医生定期对您是否仍然需要这种待遇。

Inform your doctor if your condition persists or worsens.通知你的医生如果您的条件依然存在或恶化。

What conditions does this medication treat? 什么样的条件，这药物治疗？

Amitiza Oral is used to treat the following: Amitiza口服用于治疗如下：

Chronic Difficulty having a Bowel Movement慢性难有大便

Side Effects 副作用

Nausea, diarrhea, gas, vomiting, dry mouth, runny nose, cough, fever, headache, dizziness, joint/back pain, or trouble sleeping may occur.恶心，腹泻，天然气，呕吐，口干，流鼻涕，咳嗽，发烧，头痛，头晕，关节/背痛，失眠或可能发生的。 If any of these effects persist or worsen, notify your doctor or pharmacist promptly.如果这些影响持续或恶化，通知您的医生或药剂师迅速。

Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.请记住，您的医生处方用药，因为这有利于你是大于风险的副作用。 Many people using this medication do not have serious side effects.很多人利用这一药品没有严重的副作用。

Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling of arms/legs, mental/mood changes, chest pain.告诉您的医生立即如果任何这些不太可能，但严重的副作用发生：肿胀的武器/腿，精神/情绪的变化，胸痛。

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.一个非常严重的过敏反应，这种药物是不可能的，但也立即寻求医疗照顾，如果它发生。 Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.症状严重的过敏反应可能包括：皮疹，发痒，肿胀，严重的头晕，呼吸困难。

This is not a complete list of possible side effects.这不是一个完整名单可能带来的副作用。 If you notice other effects not listed above, contact your doctor or pharmacist.如果您发现其他效果没有在上面列出，请联系您的医生或药剂师。

Does Amitiza Oral have any side effects? Amitiza口腔是否有任何副作用？

The following side effects are associated with Amitiza Oral:下面的副作用与口服Amitiza ：

Common side effects: 常见的副作用：

Head Pain头疼痛	Severe严重
Dizzy头晕目眩	Less Severe那么严重
Feel Like Throwing Up感觉要吐了	Less Severe那么严重
Diarrhea腹泻	Less Severe那么严重
Stomach Cramps胃痉挛	Less Severe那么严重

Infrequent side effects: 罕见的副作用：

Depression抑郁症	Severe严重
Urinary Tract Infection尿路感染	Severe严重
Joint Pain关节疼痛	Severe严重
Backache背痛	Severe严重
Foot Pain足部疼痛	Severe严重
Fluid Retention in the Legs, Feet, Arms or Hands饮的腿，脚，武器或手	Severe严重
Trouble Breathing呼吸困难	Severe严重
Swelling of the Abdomen肿胀的腹部	Severe严重
Throat Irritation喉咙刺激性	Less Severe那么严重
Acute Infection of the Nose, Throat or Sinus急性感染的鼻，喉或窦	Less Severe那么严重
Sinus Irritation and Congestion窦刺激和拥塞	Less Severe那么严重
The Flu流感	Less Severe那么严重
Condition in which Stomach Acid is Pushed Into the Esophagus条件，其中胃酸是被推入食道	Less Severe那么严重
Indigestion消化不良	Less Severe那么严重
Abnormal Trouble Sleeping异常失眠	Less Severe那么严重
Low Energy低能	Less Severe那么严重
Cough咳嗽	Less Severe那么严重
Throwing Up投掷涨	Less Severe那么严重
Gas燃气	Less Severe那么严重
Loose Stools松散粪便	Less Severe那么严重
Anxious焦虑	Less Severe那么严重

Rare side effects: 罕见的副作用：

Viral Gastroenteritis病毒性胃肠炎	Severe严重
Asthma哮喘	Severe严重
Hives蜂巢	Severe严重
Feeling Faint微弱的感觉	Severe严重
Numbness麻木	Severe严重
Rash皮疹	Severe严重
Visible Water Retention可见保水	Severe严重
Chest Pain胸痛	Severe严重
Chest Tightness胸闷	Severe严重
Unable to Control Bowel Movement无法控制大便	Severe严重
Not Feeling Well不舒服	Severe严重
Dry Mouth口干	Less Severe那么严重
Incomplete or Infrequent Bowel Movements不完整或很少大便	Less Severe那么严重
Infection caused by a Virus感染由病毒引起的	Less Severe那么严重
Cramps抽筋	Less Severe那么严重
Sensation of Spinning or Whirling感觉纺纱或旋转	Less Severe那么严重
Excessive Sweating多汗	Less Severe那么严重
Chills冷	Less Severe那么严重
Involuntary Quivering自愿颤抖	Less Severe那么严重
Taste Problems趣味问题	Less Severe那么严重
Temporary Redness of Face and Neck临时发红的脸和颈部	Less Severe那么严重
Loss of Appetite食欲不振	Less Severe那么严重
Weight Gain体重增加	Less Severe那么严重
Heart Throbbing or Pounding心Throbbing或碰撞	Less Severe那么严重
Nervous神经	Less Severe那么严重
Numbness and Tingling麻木和刺痛	Less Severe那么严重
Feeling Weak感觉身体虚弱	Less Severe那么严重

Precautions 防范措施

Before taking lubiprostone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.在采取lubiprostone ，请告诉您的医生或药剂师如果你是过敏的情况;或者，如果您有任何其他过敏。

This medication should not be used if you have certain medical conditions.这种药物不应当被用来如果您有一定的医疗条件。 Before using this medicine, consult your doctor or pharmacist if you have: a severe stomach condition (mechanical bowel obstruction).在使用这种药，咨询您的医生或药剂师如果您有：一个严重的胃病，条件（机械性肠梗阻）。

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe diarrhea.在使用这种药物，请告诉您的医生或药剂师您的医学史，特别是：严重腹泻。

This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.这种药物可以使你头晕目眩;使用谨慎从事，需要警觉，如驾驶或使用机器。 Limit alcoholic beverages.限制含酒精饮料。

This medication is not recommended for use during pregnancy.这种药物是不建议在怀孕期间使用。 Women of childbearing age should have a negative pregnancy test before starting this medication.育龄妇女应该有一个阴性怀孕测试开始之前服药。 Also, women should use an effective form of birth control while taking this medication.此外，妇女应该使用的一种有效形式节育同时这一药物。 Consult your doctor for more details.咨询你的医生以获得更多详情。

It is not known whether this drug passes into breast milk.目前还不清楚这种药物是否通行证进入母乳。 Therefore, breast-feeding while using this medication is not recommended.因此，母乳喂养而使用这种药物是不推荐。 Consult your doctor before breast-feeding.你的医生咨询之前，母乳喂养。

Interactions 互动

Your healthcare professionals (eg, doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.您的医护专业人员（如医生或药剂师）可能已经意识到任何可能的药物相互作用，可能是监测你。 Do not start, stop or change the dosage of any medicine before checking with them first.不要启动，停止或改变剂量任何药物检查前与他们第一次。

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.在使用这种药物，请告诉您的医生或药剂师的所有处方药和非处方/草药产品可以使用。

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.请列出您所有的药物与你分享的名单和你的医生和药剂师。

overdose 过量

If overdose is suspected, contact your local poison control center or emergency room immediately.如果过量怀疑，请联络您当地中毒控制中心或急诊室立即。 US residents can call the US national poison hotline at 1-800-222-1222.美国居民可致电美国国家毒物热线1-800-222-1222 。 Canadian residents should call their local poison control center directly.加拿大居民应要求其当地中毒控制中心直接联系。 Symptoms of overdose may include: fainting, flushing, paleness, loss of appetite, sweating.过量的症状可能包括：昏厥，冲厕，脸色苍白，食欲不振，出汗。

NOTES: 注意事项：

Do not share this medication with others.不共用与其他药物。

MISSED DOSE: 错过剂量：

If you miss a dose, take it as soon as you remember.如果你错过的剂量，是否可以尽快你还记得。 If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.如果是附近的下一次剂量，跳过错过剂量和恢复您的正常用药时间表。 Do not double the dose to catch up.不要一倍剂量，迎头赶上。

STORAGE: 存储：

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.储存在室温为77华氏度（ 25摄氏度）以外的轻型和水分。 Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.存储简之间的59-86华氏度（ 15-30摄氏度）是允许的。 Do not store in the bathroom.不要储存在浴室。 Keep all medicines away from children and pets.保留所有药品远离儿童和宠物。

Properly discard this product when it is expired or no longer needed.妥善弃置此产品时，已过期或不再需要。 Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.咨询您的药剂师或当地废物处理公司的更详细的资料如何安全舍弃您的产品。