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Breast Cancer: Sentinel Node Biopsy乳腺癌:前哨淋巴结活检 PDF格式 打印 电子邮箱
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Monday, 24 December 2007星期一, 2007年12月24日

Sentinel node biopsy is a relatively new way of pinpointing the first few lymph nodes into which a tumor drains (called the "sentinel" node).前哨淋巴结活检是一个相对较新的方式精确的头几个淋巴结成一个肿瘤排水沟(所谓的“哨兵”节点) 。 This helps doctors remove only those nodes of the lymphatic system most likely to contain cancer cells.这有助于医生只有消除这些节点的淋巴系统最有可能含有癌细胞。 The sentinel nodes are the first place that cancer is likely to spread.前哨淋巴结是第一名,癌症有可能扩散。

In breast cancer, the sentinel node is usually located in the axillary nodes, under the arm.在患乳腺癌,前哨淋巴结通常位于腋窝淋巴结,下手臂。 In a small percentage of cases, the sentinel node is found somewhere else in the lymphatic system of the breast.在一个很小比例的情况下,前哨淋巴结是在其他地方发现的淋巴系统的乳腺癌。 If the sentinel node is positive there may be other positive lymph nodes upstream.如果前哨淋巴结是积极的可能还有其他积极的上游淋巴结。 If it is negative, it is highly likely that all of the upstream nodes are negative.如果是否定的,但是它极有可能,所有的上游节点是否定的。

How is the Procedure Performed?是如何演出的程序?

To locate the sentinel nodes, a labeling substance, either radioactive tracer, blue dye or both is injected into the area around the tumor before a mastectomy or lumpectomy is performed.如果要找出前哨淋巴结,标签内容,或者放射性示踪,蓝染料或两者注入周围地区的肿瘤术前或进行乳房肿瘤切除术。 The tracer travels the same path to the lymph nodes that the cancer cells would take, making it possible for the surgeon to determine the one or two nodes most likely to test positive for cancer by either visualizing the color or using a hand held Geiger counter.示踪旅行相同的路径至淋巴结的癌细胞将采取,使外科医生,以确定一个或两个节点最有可能试验阳性的癌症由可视化的颜色或使用手提盖格计数器。

This method varies in how it is performed among hospitals and is still being tested to determine the best way to identify the positive nodes.这种方法有所不同,如何进行各医院,目前仍在进行测试,以确定最佳途径,确定了积极的节点。

What are the Advantages of This Method?有哪些优势这种方法?

Research suggests that the sentinel node biopsy procedure can be useful in determining which lymph nodes to remove, without the risk of complications associated with surgically removing all potentially cancerous nodes.研究表明,前哨淋巴结活检的程序可用于确定哪些淋巴结清除,但并发症的风险与手术消除所有潜在的癌变节点。

When a lumpectomy or mastectomy is performed, only a few lymph nodes are removed for laboratory analysis using the sentinel node biopsy technique.当一个乳房肿瘤切除术或乳房进行,只有少数淋巴结清除的实验室分析用前哨淋巴结活检技术。 In traditional lumpectomy or mastectomy procedures, a greater number of the axillary nodes are removed, which can lead to complications after surgery such lymphedema.在传统的乳房肿瘤切除术或乳房切除术的程序,有更多的腋窝淋巴结清除,从而导致手术后的并发症等淋巴水肿。

Reviewed by the doctors at The Cleveland Clinic Taussig Cancer Center .审查由医生在克利夫兰诊所陶癌症研究中心

VitaDocs Medical Reference provided in collaboration with the Cleveland Clinic VitaDocs提供医学参考与克利夫兰诊所

Edited by Paul O'Neill, MD on September 01, 2006编辑保罗奥尼尔,医学博士于2006年9月1号

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